VortexSort Continuous-Flow Acoustofluidic Cell Separation System

Product Introduction

VortexSort cell separation system uses high-frequency acoustic technology，generates stable 3D vortex flow fields in microchannels，for high-precision cell manipulationNo centrifugation or labeling needed — efficiently removes contaminating particles and optimizes sample quality. Compatible with downstream cell sorting, flow cytometry, and single-cell sequencing.

Two Core Functions：

① Precise target cell isolation — no fluorescent labeling needed，continuously separates and enriches specific cells from whole blood。

② Efficient OptimizationSampleQuality — No centrifugation — easily removes debris, dead cells, and other contaminating particles.

WideParticle Range

by tuning acoustic parametersenables 200nm–50μm micro/nano particle separation。

HighThroughput

processes up to3different samples in parallel，or multiple rounds of purification on the same sample/Concentration，Throughput 10–100 μL/min。

LowSampleVolume

sample volume as low as microliters。

Non-Destructive Separation

Acoustofluidic-driven cell manipulation — gentle process preserving cell viability and function.

Sterile Single-Use

eliminates cross-contaminationandaerosols，safeguarding sample quality and operator safety。

Direct Post-Separation Culture

buffer options include PBS、sterile water、cell culture media, etc.，no additional purification needed after separation。

Application Examples

Applications 1：Plasma Exchange

Pain Point

Clinical plasma separation via centrifugation or membrane filtration suffers from mechanical cell damage, membrane clogging, poor biocompatibility, and difficulty in miniaturization.

VortexSort Solution

acoustofluidic technology uses sound-field-induced acoustic streaming vortices，YesContact-free、low-damageenables efficient blood cell-plasma separation with advantages of being label-free, gentle, controllable, and easily miniaturized.

Applications 2：OrganoidSamplePrecision Purification

Pain Point

large amounts of cell debris from organoid pre-processing、Matrigel residue severely interferes with downstream sequencing and functional assaysTraditional centrifugation and filtration cause significant damage, low precision, and lack standardization.

VortexSort Solution

using acoustic vortexContact-freemanipulation，gently separates single-cell suspensions from debris、residue separation，processautomation、standardized。rat lung tissue cell proportion increased from 31.5% to 78.8%，debris from 68.5% to 21.2%。rat brain cell proportion 67.6% to 94.9%。