Micromanipulation · Micromanipulation
Gigahertz hypersonic MicroJet"MicroJets"，enablesContact-freesingle-cell precision injection, sorting, and affinity detection.AI AI vision with full automation for efficient selection-to-recoveryfull workflowclosed-loop。
MicroJetsMicromanipulationSystemis based on Hypersonic（Hypersound）technology, using gigahertz-frequency acoustic waves to generate"MicroJets"for contact-free, single-cell precision injection, sorting, and affinity detection. The system integrates AI AI vision recognition with full automation for efficient cell selection, manipulation, analysis, and recovery —full workflowclosed-loop。
Hypersonic waves generate instantaneous microscale jets in liquid environments — "MicroJets"with jet diameters of only tens of microns and speeds up to 10 m/m/s, delivering thousands of impacts per second. This"fast, precise, dense""Micro Water-Hammer"effect ensures high cell viability while delivering exceptional experimental reproducibility.
Virtual water-jet replaces solid needles, completely avoiding membrane puncture damage and cross-contamination.Cell ViabilityMaintaining ≥90%。
No needle changes, no washing, no clogging risk — reducing reliance on skilled operators.
Thousands of impacts per second — single-cell operations in seconds with automated batch processing.
impact force 1 pN–0.1 mN adjustable，PositioningAccuracySuperior 10μm，with AI visionenablesfull auto path planning。
using hypersonic excitation"MicroJets"delivers thousands of instantaneous, controllable impacts per second to the cell membrane via the"Micro Water-Hammer"effect, gently opening transmembrane channels without physical puncture. Widely applicable to gene editing, transgenics, and cell biology (protein, drug, or inhibitor delivery). Optional drug dosage control probe and fluid control module for precise drug delivery.
using hypersonic probe-generated"Micro Water-Knife"(a high-frequency, controllable localized shear force) for contact-free single-cell precision. Applies 1 pN–0.1 mN shear force，1–1000 Hz adjustable frequency, with real-time recording of force magnitude, frequency, duration, and cell interface detachment for precise quantification of dynamic cell affinity. No fluorescent or magnetic labeling needed — cells remain in their natural state.
Applications：Structural biology, drug screening, immune cell sorting (TCRAffinityandForcesorting）、Cell Adhesion Measurement、CGT high-affinityandForce CAR-T sorting、Microbe Selection。
Delivers pulsed or sustained mechanical stimulation to individual cells with force (1 pN–0.1 mN), frequency (up to thousands/sec), and mode all programmable. Applications include directed stem cell differentiation, subcellular mechanical perturbation, cell function activation (neurons/immune cells/cardiomyocytes）、mechanotransduction research（Piezo1/2、TRPchannels）、Cell MigrationandInvasion Regulation。
ExperienceMicroJetsPrecisionandGentle — from injection to sorting，one-clickautomation
